Pilot Projects

Approved Projects

Improving Dental Cellular Tissue Imaging through Multi-Methodical Micro-CT Imaging

Today there is a gap in understanding the interdependence between soft and hard tissue in for example human bone and teeth – processes that are central to fixation, repair, and biomaterial-cell interactions. Hence, understanding these processes is important from a clinical perspective and ultimately can help impact patient care.

This HALRIC pilot project addresses key challenges in imaging the structural complexities of bones, teeth, and associated soft tissues by leveraging contrast-enhanced micro-CT and synchrotron techniques. By combining state-of-the-art technologies like phase-contrast imaging and X-ray fluorescence mapping, the project seeks to improve the standardization and reliability of non-destructive imaging techniques, enabling more precise visualization of cellular structures and their interactions within hard and soft tissues.

The initiative is a cross-border collaboration between researchers and clinicians from Lund University, Malmö University, and the University of Oslo. It fosters an interdisciplinary approach, utilizing cutting-edge research infrastructures, including MAX IV in Sweden, Elettra Sincrotrone in Italy, and SOLEIL Synchrotron in France. These efforts integrate expertise in X-ray imaging, life sciences, and clinical applications to push the boundaries of biomedical imaging.

The project’s outcomes are expected to improve patient treatment by enabling more precise diagnostics and targeted therapies in dental and orthopedic care.

For further information about this HALRIC pilot project, please contact:

Håvard J. Haugen, University of Oslo

h.j.haugen@odont.uio.no

Starting date:
01 Jan, 2025

Research infrastructures:

  • microCT at University of Oslo
  • SOLEIL Synchrotron
  • Elettra Sincrotrone
  • MAX IV

HALRIC partners:

  • University of Oslo
  • Malmö University
  • MAX IV

Project participants:

  • Andreas Stavropoulos
  • Håvard J. Haugen
  • Liebert Parreiras Nogueira
  • Maik Kahnt
  • Torben Hildebrand